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The decrease in blood pressure was most notable approximately 1—2 hours after dosing, and was not different from placebo at 8 hours.
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Treatment with intravenous epoprostenol, intravenous or inhaled iloprost, or subcutaneous treprostinil was prohibited.
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This evidence summary is based on the best available evidence for using sildenafil to manage digital ulcers in people with systemic sclerosis, including 2 small RCTs Fries et al.


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10mg × 10 tablet$ 22.95$ 3.00Add to cart
10mg × 20 tablet$ 45.95$ 2.50$ 9.95Add to cart
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20mg × 10 tablet$ 32.95$ 3.00Add to cart
20mg × 20 tablet$ 66.95$ 2.50$ 9.95Add to cart
20mg × 30 tablet$ 90.95$ 2.10$ 26.95Add to cart
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20mg × 90 tablet$ 210.95$ 1.70$ 111.95Add to cart
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40mg × 10 tablet$ 44.95$ 3.00Add to cart
40mg × 20 tablet$ 72.95$ 2.50$ 10.95Add to cart
40mg × 30 tablet$ 92.95$ 2.10$ 27.95Add to cart
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80mg × 30 tablet$ 136.95$ 2.10$ 26.95Add to cart
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100mg × 20 tablet$ 45.95$ 2.50$ 9.95Add to cart
100mg × 30 tablet$ 57.95$ 2.10$ 27.95Add to cart
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